Drugs Information: Ketoconazole

Basic Information

ID DDInter1008
Drug Type small molecule
Molecular Formula C26H28Cl2N4O4
Molecular Weight 531.440
Description Ketoconazole is a broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
ATC Classification G01AF11 G01AF20 J02AB02 D01AC08
IUPAC Name 1-[4-(4-{[2-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Ylmethyl)-1,3-Dioxolan-4-Yl]Methoxy}Phenyl)Piperazin-1-Yl]Ethan-1-One
InChI Inchi=1S/C26H28Cl2N4O4/C1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/H2-9,14,18,23H,10-13,15-17H2,1H3
InChI Key XMAYWYJOQHXEEK-UHFFFAOYSA-N
Canonical SMILES CC(=O)N1CCN(CC1)C1=CC=C(OCC2COC(CN3C=CN=C3)(O2)C2=CC=C(Cl)C=C2Cl)C=C1
Useful Links DrugBank ChEMBL PubChem

Interactions with Ketoconazole

Severity level ID Name Mechanism Detail