Drugs Information: Ledipasvir
Basic Information
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| ID | DDInter1031 | |
| Drug Type | small molecule | |
| Molecular Formula | C49H54F2N8O6 | |
| Molecular Weight | 889.017 | |
| Description | Ledipasvir is a direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. | |
| ATC Classification | J05AP51 | |
| IUPAC Name | Methyl N-[(2S)-1-[(6S)-6-[4-(9,9-Difluoro-7-{2-[(1R,3S,4S)-2-[(2S)-2-[(Methoxycarbonyl)Amino]-3-Methylbutanoyl]-2-Azabicyclo[2.2 | |
| InChI | Inchi=1S/C49H54F2N8O6/C1-24(2)39(56-46(62)64-5)44(60)58-23-48(15-16-48)21-38(58)42-52-22-37(55-42)28-9-13-32-31-12-8-26(18-33(31)49(50,51)34(32)19-28)27-10-14-35-36(20-27)54-43(53-35)41-29-7-11-30(17-29)59(41)45(61)40(25(3)4)57-47(63)65-6/H8-10,12-14,18-20,22,24-25,29-30,38-41H,7,11,15-17,21,23H2,1-6H3,(H,52,55)(H,53,54)(H,56,62)(H,57,63)/T29-,30+,38-,39-,40-,41-/M0/S1 | |
| InChI Key | VRTWBAAJJOHBQU-KMWAZVGDSA-N | |
| Canonical SMILES | COC(=O)N[C@@H](C(C)C)C(=O)N1CC2(CC2)C[C@H]1C1=NC(=CN1)C1=CC=C2C3=CC=C(C=C3C(F)(F)C2=C1)C1=CC=C2NC(=NC2=C1)[C@@H]1[C@H]2CC[C@H](C2)N1C(=O)[C@@H](NC(=O)OC)C(C)C | |
| Useful Links | DrugBank ChEMBL PubChem | |
Interactions with Ledipasvir
| Severity level | ID | Name | Mechanism | Detail |
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