Drugs Information: Leflunomide

Basic Information

ID DDInter1033
Drug Type small molecule
Molecular Formula C12H9F3N2O2
Molecular Weight 270.210
Description Leflunomide is a pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
ATC Classification L04AA13
IUPAC Name 5-Methyl-N-[4-(Trifluoromethyl)Phenyl]-1,2-Oxazole-4-Carboxamide
InChI Inchi=1S/C12H9F3N2O2/C1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/H2-6H,1H3,(H,17,18)
InChI Key VHOGYURTWQBHIL-UHFFFAOYSA-N
Canonical SMILES CC1=C(C=NO1)C(=O)NC1=CC=C(C=C1)C(F)(F)F
Useful Links DrugBank ChEMBL PubChem

Interactions with Leflunomide

Severity level ID Name Mechanism Detail