Drugs Information: Lenvatinib

Basic Information

ID DDInter1036
Drug Type small molecule
Molecular Formula C21H19Cln4O4
Molecular Weight 426.860
Description Lenvatinib is a receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
ATC Classification L01XE29
IUPAC Name 4-{3-Chloro-4-[(Cyclopropylcarbamoyl)Amino]Phenoxy}-7-Methoxyquinoline-6-Carboxamide
InChI Inchi=1S/C21H19Cln4O4/C1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/H4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)
InChI Key WOSKHXYHFSIKNG-UHFFFAOYSA-N
Canonical SMILES COC1=C(C=C2C(OC3=CC=C(NC(=O)NC4CC4)C(Cl)=C3)=CC=NC2=C1)C(N)=O
Useful Links DrugBank ChEMBL PubChem

Interactions with Lenvatinib

Severity level ID Name Mechanism Detail