Drugs Information: Lesinurad

Basic Information

ID DDInter1038
Drug Type small molecule
Molecular Formula C17H14Brn3O2S
Molecular Weight 404.288
Description Lesinurad is a uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy.
ATC Classification M04AB05
IUPAC Name 2-{[5-Bromo-4-(4-Cyclopropylnaphthalen-1-Yl)-4H-1,2,4-Triazol-3-Yl]Sulfanyl}Acetic Acid
InChI Inchi=1S/C17H14Brn3O2S/C18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/H1-4,7-8,10H,5-6,9H2,(H,22,23)
InChI Key FGQFOYHRJSUHMR-UHFFFAOYSA-N
Canonical SMILES OC(=O)CSC1=NN=C(Br)N1C1=CC=C(C2CC2)C2=C1C=CC=C2
Useful Links DrugBank ChEMBL PubChem

Interactions with Lesinurad

Severity level ID Name Mechanism Detail