Drugs Information: Meclizine

Basic Information

ID DDInter1134
Drug Type small molecule
Molecular Formula C25H27Cln2
Molecular Weight 390.958
Description Meclizine is a histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness.
ATC Classification R06AE55 R06AE05
IUPAC Name 1-[(4-Chlorophenyl)(Phenyl)Methyl]-4-[(3-Methylphenyl)Methyl]Piperazine
InChI Inchi=1S/C25H27Cln2/C1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23/H2-13,18,25H,14-17,19H2,1H3
InChI Key OCJYIGYOJCODJL-UHFFFAOYSA-N
Canonical SMILES CC1=CC(CN2CCN(CC2)C(C2=CC=CC=C2)C2=CC=C(Cl)C=C2)=CC=C1
Useful Links DrugBank ChEMBL PubChem

Interactions with Meclizine

Severity level ID Name Mechanism Detail