|
| ID |
DDInter1188 |
| Drug Type |
small molecule |
| Molecular Formula |
C21H26No4 |
| Molecular Weight |
356.442
|
| Description |
Methylnaltrexone is a μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy.
|
| ATC Classification |
A06AH01
|
| IUPAC Name |
(1S,4R,5R,13R,17S)-4-(Cyclopropylmethyl)-10,17-Dihydroxy-4-Methyl-14-Oxo-12-Oxa-4-Azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]Octadeca |
| InChI |
Inchi=1S/C21H25No4/C1-22(11-12-2-3-12)9-8-20-17-13-4-5-14(23)18(17)26-19(20)15(24)6-7-21(20,25)16(22)10-13/H4-5,12,16,19,25H,2-3,6-11H2,1H3/P+1/T16-,19+,20+,21-,22-/M1/S1 |
| InChI Key |
JVLBPIPGETUEET-WIXLDOGYSA-O |
| Canonical SMILES |
C[N@+]1(CC2CC2)CC[C@]23[C@H]4OC5=C(O)C=CC(C[C@@H]1[C@]2(O)CCC4=O)=C35 |
| Useful Links |
DrugBank
PubChem
|