Drugs Information: Metolazone

Basic Information

ID DDInter1199
Drug Type small molecule
Molecular Formula C16H16Cln3O3S
Molecular Weight 365.841
Description Metolazone is a thiazide-like diuretic used to treat hypertension.
ATC Classification C03EA12 G01AE10 C03BA08
IUPAC Name 7-Chloro-2-Methyl-3-(2-Methylphenyl)-4-Oxo-1,2,3,4-Tetrahydroquinazoline-6-Sulfonamide
InChI Inchi=1S/C16H16Cln3O3S/C1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/H3-8,10,19H,1-2H3,(H2,18,22,23)
InChI Key AQCHWTWZEMGIFD-UHFFFAOYSA-N
Canonical SMILES CC1NC2=CC(Cl)=C(C=C2C(=O)N1C1=CC=CC=C1C)S(N)(=O)=O
Useful Links DrugBank ChEMBL PubChem

Interactions with Metolazone

Severity level ID Name Mechanism Detail