Drugs Information: Oliceridine

Basic Information

ID DDInter1329
Drug Type small molecule
Molecular Formula C22H30N2O2S
Molecular Weight 386.560
Description Oliceridine is a biased opioid agonist indicated for the management of severe acute pain in adult patients. Through preferential activation of G-protein-coupled signalling pathways, oliceridine provides analgesic effect with a comparable or improved safety profile over conventional opioid agonists.
ATC Classification -
IUPAC Name [(3-Methoxythiophen-2-Yl)Methyl]({2-[(9R)-9-(Pyridin-2-Yl)-6-Oxaspiro[4.5]Decan-9-Yl]Ethyl})Amine
InChI Inchi=1S/C22H30N2O2S/C1-25-18-7-15-27-19(18)16-23-13-10-21(20-6-2-5-12-24-20)11-14-26-22(17-21)8-3-4-9-22/H2,5-7,12,15,23H,3-4,8-11,13-14,16-17H2,1H3/T21-/M1/S1
InChI Key DMNOVGJWPASQDL-OAQYLSRUSA-N
Canonical SMILES COC1=C(CNCC[C@]2(CCOC3(CCCC3)C2)C2=NC=CC=C2)SC=C1
Useful Links DrugBank ChEMBL

Interactions with Oliceridine

Severity level ID Name Mechanism Detail