Drugs Information: Palonosetron

Basic Information

ID DDInter1382
Drug Type small molecule
Molecular Formula C19H24N2O
Molecular Weight 296.414
Description Palonosetron is a serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting.
ATC Classification A04AA55 A04AA05
IUPAC Name (5S)-3-[(3S)-1-Azabicyclo[2.2.2]Octan-3-Yl]-3-Azatricyclo[7.3.1.0⁵,¹³]Trideca-1(12),9(13),10-Trien-2-One
InChI Inchi=1S/C19H24N2O/C22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20/H2,4,6,13,15,17H,1,3,5,7-12H2/T15-,17-/M1/S1
InChI Key CPZBLNMUGSZIPR-NVXWUHKLSA-N
Canonical SMILES [H][C@]12CCCC3=C1C(=CC=C3)C(=O)N(C2)[C@@H]1CN2CCC1CC2
Useful Links DrugBank ChEMBL PubChem

Interactions with Palonosetron

Severity level ID Name Mechanism Detail