Drugs Information: Pazopanib

Basic Information

ID DDInter1400
Drug Type small molecule
Molecular Formula C21H23N7O2S
Molecular Weight 437.528
Description Pazopanib is an antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
ATC Classification L01XE11
IUPAC Name 5-({4-[(2,3-Dimethyl-2H-Indazol-6-Yl)(Methyl)Amino]Pyrimidin-2-Yl}Amino)-2-Methylbenzene-1-Sulfonamide
InChI Inchi=1S/C21H23N7O2S/C1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/H5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)
InChI Key CUIHSIWYWATEQL-UHFFFAOYSA-N
Canonical SMILES CN(C1=CC2=NN(C)C(C)=C2C=C1)C1=CC=NC(NC2=CC=C(C)C(=C2)S(N)(=O)=O)=N1
Useful Links DrugBank ChEMBL PubChem

Interactions with Pazopanib

Severity level ID Name Mechanism Detail