Drugs Information: Perampanel

Basic Information

ID DDInter1428
Drug Type small molecule
Molecular Formula C23H15N3O
Molecular Weight 349.393
Description Perampanel is a non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy.
ATC Classification N03AX22
IUPAC Name 2-{6'-Oxo-1'-Phenyl-1',6'-Dihydro-[2,3'-Bipyridine]-5'-Yl}Benzonitrile
InChI Inchi=1S/C23H15N3O/C24-15-17-8-4-5-11-20(17)21-14-18(22-12-6-7-13-25-22)16-26(23(21)27)19-9-2-1-3-10-19/H1-14,16H
InChI Key PRMWGUBFXWROHD-UHFFFAOYSA-N
Canonical SMILES O=C1N(C=C(C=C1C1=CC=CC=C1C#N)C1=NC=CC=C1)C1=CC=CC=C1
Useful Links DrugBank ChEMBL PubChem

Interactions with Perampanel

Severity level ID Name Mechanism Detail