Drugs Information: Avatrombopag

Basic Information

ID DDInter143
Drug Type small molecule
Molecular Formula C29H34Cl2N6O3S2
Molecular Weight 649.668
Description Avatrombopag is a thrombopoietin receptor agonist used to treat thrombocytopenia in patients with chronic liver disease who are scheduled to undergo a procedure.
ATC Classification B02BX08
IUPAC Name 1-(3-Chloro-5-{[4-(4-Chlorothiophen-2-Yl)-5-(4-Cyclohexylpiperazin-1-Yl)-1,3-Thiazol-2-Yl]Carbamoyl}Pyridin-2-Yl)Piperidine-4-Ca
InChI Inchi=1S/C29H34Cl2N6O3S2/C30-20-15-23(41-17-20)24-27(37-12-10-35(11-13-37)21-4-2-1-3-5-21)42-29(33-24)34-26(38)19-14-22(31)25(32-16-19)36-8-6-18(7-9-36)28(39)40/H14-18,21H,1-13H2,(H,39,40)(H,33,34,38)
InChI Key OFZJKCQENFPZBH-UHFFFAOYSA-N
Canonical SMILES OC(=O)C1CCN(CC1)C1=C(Cl)C=C(C=N1)C(=O)NC1=NC(C2=CC(Cl)=CS2)=C(S1)N1CCN(CC1)C1CCCCC1
Useful Links DrugBank ChEMBL PubChem

Interactions with Avatrombopag

Severity level ID Name Mechanism Detail