Drugs Information: Phenindamine

Basic Information

ID DDInter1441
Drug Type small molecule
Molecular Formula C19H19N
Molecular Weight 261.368
Description Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold. Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.
ATC Classification R06AX04
IUPAC Name 2-Methyl-9-Phenyl-1H,2H,3H,4H,9H-Indeno[2,1-C]Pyridine
InChI Inchi=1S/C19H19N/C1-20-12-11-16-15-9-5-6-10-17(15)19(18(16)13-20)14-7-3-2-4-8-14/H2-10,19H,11-13H2,1H3
InChI Key ISFHAYSTHMVOJR-UHFFFAOYSA-N
Canonical SMILES CN1CCC2=C(C1)C(C1=CC=CC=C21)C1=CC=CC=C1
Useful Links DrugBank ChEMBL PubChem

Interactions with Phenindamine

Severity level ID Name Mechanism Detail