Drugs Information: Plecanatide
Basic Information
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| ID | DDInter1483 | |
| Drug Type | small molecule | |
| Molecular Formula | C65H104N18O26S4 | |
| Molecular Weight | - | |
| Description | Plecanatide is a laxative used to treat chronic idiopathic constipation and IBS with constipation. | |
| ATC Classification | A06AX07 | |
| IUPAC Name | (4S)-4-{[(2S)-2-{[(2S)-2-Amino-1-Hydroxy-3-(C-Hydroxycarbonimidoyl)Propylidene]Amino}-3-Carboxy-1-Hydroxypropylidene]Amino}-4-{[ | |
| InChI | Inchi=1S/C65H104N18O26S4/C1-25(2)15-34-55(98)80-41-24-113-110-21-38(58(101)77-37(65(108)109)16-26(3)4)71-44(87)20-69-62(105)50(30(10)84)83-61(104)40(78-51(94)29(9)70-63(106)48(27(5)6)81-57(100)35(18-43(68)86)76-64(107)49(28(7)8)82-60(41)103)23-112-111-22-39(59(102)73-32(53(96)75-34)11-13-45(88)89)79-54(97)33(12-14-46(90)91)72-56(99)36(19-47(92)93)74-52(95)31(66)17-42(67)85/H25-41,48-50,84H,11-24,66H2,1-10H3,(H2,67,85)(H2,68,86)(H,69,105)(H,70,106)(H,71,87)(H,72,99)(H,73,102)(H,74,95)(H,75,96)(H,76,107)(H,77,101)(H,78,94)(H,79,97)(H,80,98)(H,81,100)(H,82,103)(H,83,104)(H,88,89)(H,90,91)(H,92,93)(H,108,109)/T29-,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,48-,49-,50-/M0/S1 | |
| InChI Key | NSPHQWLKCGGCQR-DLJDZFDSSA-N | |
| Canonical SMILES | [H][C@@]12CSSC[C@H](NC(=O)CNC(=O)[C@@]([H])(NC(=O)[C@]([H])(CSSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC2=O)C(C)C)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(O)=O | |
| Useful Links | DrugBank ChEMBL PubChem | |
Interactions with Plecanatide
| Severity level | ID | Name | Mechanism | Detail |
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