Drugs Information: Potassium perchlorate

Basic Information

ID DDInter1501
Drug Type small molecule
Molecular Formula Clko4
Molecular Weight -
Description Potassium perchlorate is an inorganic salt with the chemical formula KClO4. It is a strong oxidizer with the lowest solubility of the alkali metal perchlorates. Potassium is most commonly used in flares and automobile airbags [A32609]. The use of potassium perchlorate as a component in sealing gaskets for food containers has been revoked by the FDA following the use being abandoned by the industry [L2365]. Potassium perchlorate acts as a competitive inhibitor of iodine uptake by the thyroid gland and attenuates the production of the thyroid hormone. Thus the use of potassium perchlorate has been extensive for hyperthyroidism during the last 50 years, particularly in the late 1950s and early 1960s [A32609]. The therapeutic use of potassium perchlorate in thyroid disorders has been ceased due to a high risk for developing aplastic anemia and nephrotic syndrome [L2364].
ATC Classification H03BC01
IUPAC Name Potassium Perchlorate
InChI Inchi=1S/Clho4.K/C2-1(3,4)5;/H(H,2,3,4,5);/Q;+1/P-1
InChI Key YLMGFJXSLBMXHK-UHFFFAOYSA-M
Canonical SMILES [K+].[O-][Cl](=O)(=O)=O
Useful Links DrugBank ChEMBL PubChem

Interactions with Potassium perchlorate

Severity level ID Name Mechanism Detail