Drugs Information: Propiomazine
Basic Information
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| ID | DDInter1537 | |
| Drug Type | small molecule | |
| Molecular Formula | C20H24N2Os | |
| Molecular Weight | 340.491 | |
| Description | Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. Future uses may include the treatment of obsessive-compulsive disorder and severe behavioral disorders in autism. Structurally and pharmacologically similar to clozapine, propiomazine binds to alpha(1), dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. | |
| ATC Classification | N05CM06 | |
| IUPAC Name | 1-{10-[2-(Dimethylamino)Propyl]-10H-Phenothiazin-2-Yl}Propan-1-One | |
| InChI | Inchi=1S/C20H24N2Os/C1-5-18(23)15-10-11-20-17(12-15)22(13-14(2)21(3)4)16-8-6-7-9-19(16)24-20/H6-12,14H,5,13H2,1-4H3 | |
| InChI Key | UVOIBTBFPOZKGP-UHFFFAOYSA-N | |
| Canonical SMILES | CCC(=O)C1=CC2=C(SC3=CC=CC=C3N2CC(C)N(C)C)C=C1 | |
| Useful Links | DrugBank ChEMBL PubChem | |
Interactions with Propiomazine
| Severity level | ID | Name | Mechanism | Detail |
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