|
| ID |
DDInter1576 |
| Drug Type |
small molecule |
| Molecular Formula |
C21H15Clf4N4O3 |
| Molecular Weight |
482.821
|
| Description |
Regorafenib is a kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.
|
| ATC Classification |
L01XE21
|
| IUPAC Name |
4-[4-({[4-Chloro-3-(Trifluoromethyl)Phenyl]Carbamoyl}Amino)-3-Fluorophenoxy]-N-Methylpyridine-2-Carboxamide |
| InChI |
Inchi=1S/C21H15Clf4N4O3/C1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/H2-10H,1H3,(H,27,31)(H2,29,30,32) |
| InChI Key |
FNHKPVJBJVTLMP-UHFFFAOYSA-N |
| Canonical SMILES |
CNC(=O)C1=CC(OC2=CC(F)=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)=CC=N1 |
| Useful Links |
DrugBank
ChEMBL
PubChem
|