Drugs Information: Rifabutin
Basic Information
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| ID | DDInter1589 | |
| Drug Type | small molecule | |
| Molecular Formula | C46H62N4O11 | |
| Molecular Weight | 847.019 | |
| Description | Rifabutin is an antibiotic used to treat mycobacterium avium complex disease in patients with HIV. | |
| ATC Classification | J04AB04 | |
| IUPAC Name | (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-Trihydroxy-11-Methoxy-3,7,12,14,16,18,22-Heptamethyl-1'-(2-Methylpropyl) | |
| InChI | Inchi=1S/C46H62N4O11/C1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/H12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/B13-12+,20-15+,24-14-/T23-,25+,26+,27+,30-,37-,38+,41+,45-/M0/S1 | |
| InChI Key | ATEBXHFBFRCZMA-VXTBVIBXSA-N | |
| Canonical SMILES | CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C2=O)C2=C(C(O)=C3C)C(=O)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C1NC3(CCN(CC3)CC(C)C)N=C21 | |
| Useful Links | DrugBank ChEMBL PubChem | |
Interactions with Rifabutin
| Severity level | ID | Name | Mechanism | Detail |
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