Drugs Information: Romidepsin
Basic Information
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| ID | DDInter1616 | |
| Drug Type | small molecule | |
| Molecular Formula | C24H36N4O6S2 | |
| Molecular Weight | 540.706 | |
| Description | Romidepsin is a histone deacetylase (HDAC) inhibitor used to treat cutaneous and peripheral T-cell lymphoma. | |
| ATC Classification | L01XX39 | |
| IUPAC Name | (1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-Bis(Propan-2-Yl)-2-Oxa-12,13-Dithia-5,8,20,23-Tetraazabicyclo[8.7.6]Tricos-16-Ene-3,6,9 | |
| InChI | Inchi=1S/C24H36N4O6S2/C1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/H6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/B9-7+,16-6-/T15-,17-,19-,20+/M1/S1 | |
| InChI Key | OHRURASPPZQGQM-GCCNXGTGSA-N | |
| Canonical SMILES | C\C=C1/NC(=O)[C@H]2CSSCC\C=C\[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@@H](NC1=O)C(C)C | |
| Useful Links | DrugBank ChEMBL PubChem | |
Interactions with Romidepsin
| Severity level | ID | Name | Mechanism | Detail |
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