Drugs Information: Sirolimus
Basic Information
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| ID | DDInter1678 | |
| Drug Type | small molecule | |
| Molecular Formula | C51H79No13 | |
| Molecular Weight | - | |
| Description | Sirolimus is an immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. | |
| ATC Classification | S01XA23 L04AA10 | |
| IUPAC Name | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-Hydroxy-3-Methoxycyclohexyl] | |
| InChI | Inchi=1S/C51H79No13/C1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/H11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/B13-11+,16-12+,31-17+,35-25+/T30-,32-,33-,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/M1/S1 | |
| InChI Key | QFJCIRLUMZQUOT-HPLJOQBZSA-N | |
| Canonical SMILES | [H][C@@]1(C[C@@H](C)[C@]2([H])CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@]3([H])CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@@]3([H])C(=O)O2)OC)CC[C@@H](O)[C@@H](C1)OC | |
| Useful Links | DrugBank ChEMBL PubChem | |
Interactions with Sirolimus
| Severity level | ID | Name | Mechanism | Detail |
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