Drugs Information: Sonidegib

Basic Information

ID DDInter1701
Drug Type small molecule
Molecular Formula C26H26F3N3O3
Molecular Weight 485.506
Description Sonidegib is an antineoplastic agent used for the treatment of locally advanced recurrent basal cell carcinoma (BCC) following surgery and radiation therapy, or in cases where surgery or radiation therapy are not appropriate.
ATC Classification L01XX48
IUPAC Name N-{6-[(2R,6S)-2,6-Dimethylmorpholin-4-Yl]Pyridin-3-Yl}-2-Methyl-4'-(Trifluoromethoxy)-[1,1'-Biphenyl]-3-Carboxamide
InChI Inchi=1S/C26H26F3N3O3/C1-16-14-32(15-17(2)34-16)24-12-9-20(13-30-24)31-25(33)23-6-4-5-22(18(23)3)19-7-10-21(11-8-19)35-26(27,28)29/H4-13,16-17H,14-15H2,1-3H3,(H,31,33)/T16-,17+
InChI Key VZZJRYRQSPEMTK-CALCHBBNSA-N
Canonical SMILES [H][C@]1(C)CN(C[C@@]([H])(C)O1)C1=CC=C(NC(=O)C2=CC=CC(=C2C)C2=CC=C(OC(F)(F)F)C=C2)C=N1
Useful Links DrugBank ChEMBL PubChem

Interactions with Sonidegib

Severity level ID Name Mechanism Detail