|
| ID |
DDInter1842 |
| Drug Type |
small molecule |
| Molecular Formula |
C26H23Fin5O4 |
| Molecular Weight |
615.403
|
| Description |
Trametinib is a kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
|
| ATC Classification |
L01XE25
|
| IUPAC Name |
N-(3-{3-Cyclopropyl-5-[(2-Fluoro-4-Iodophenyl)Amino]-6,8-Dimethyl-2,4,7-Trioxo-1H,2H,3H,4H,6H,7H-Pyrido[4,3-D]Pyrimidin-1-Yl}Phe |
| InChI |
Inchi=1S/C26H23Fin5O4/C1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34/H4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34) |
| InChI Key |
LIRYPHYGHXZJBZ-UHFFFAOYSA-N |
| Canonical SMILES |
CN1C(=O)C(C)=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC1=CC=C(I)C=C1F)C1=CC(NC(C)=O)=CC=C1 |
| Useful Links |
DrugBank
ChEMBL
PubChem
|