|
| ID |
DDInter1868 |
| Drug Type |
small molecule |
| Molecular Formula |
C10H11F3N2O5 |
| Molecular Weight |
296.201
|
| Description |
Trifluridine is a nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
|
| ATC Classification |
L01BC59
S01AD02
|
| IUPAC Name |
1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-5-(Trifluoromethyl)-1,2,3,4-Tetrahydropyrimidine-2,4-Dione |
| InChI |
Inchi=1S/C10H11F3N2O5/C11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/H2,5-7,16-17H,1,3H2,(H,14,18,19)/T5-,6+,7+/M0/S1 |
| InChI Key |
VSQQQLOSPVPRAZ-RRKCRQDMSA-N |
| Canonical SMILES |
OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(C(=O)NC1=O)C(F)(F)F |
| Useful Links |
DrugBank
ChEMBL
PubChem
|