|
| ID |
DDInter1925 |
| Drug Type |
small molecule |
| Molecular Formula |
C23H18Clf2N3O3S |
| Molecular Weight |
489.930
|
| Description |
Vemurafenib is a kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
|
| ATC Classification |
G01AE10
L01XE15
|
| IUPAC Name |
N-{3-[5-(4-Chlorophenyl)-1H-Pyrrolo[2,3-B]Pyridine-3-Carbonyl]-2,4-Difluorophenyl}Propane-1-Sulfonamide |
| InChI |
Inchi=1S/C23H18Clf2N3O3S/C1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/H3-8,10-12,29H,2,9H2,1H3,(H,27,28) |
| InChI Key |
GPXBXXGIAQBQNI-UHFFFAOYSA-N |
| Canonical SMILES |
CCCS(=O)(=O)NC1=C(F)C(C(=O)C2=CNC3=NC=C(C=C23)C2=CC=C(Cl)C=C2)=C(F)C=C1 |
| Useful Links |
DrugBank
ChEMBL
PubChem
|