|
| ID |
DDInter1965 |
| Drug Type |
small molecule |
| Molecular Formula |
C12H22O14Zn |
| Molecular Weight |
455.686
|
| Description |
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA [L2081]. It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.
Although it has been nasally administered for treating the common cold, this route of administration has been associated with some cases of anosmia [A32414], [A32409], [A32410], [L2080].
Studies show that zinc may be better absorbed in humans in the gluconate form [A32412], [L2105], however, results from other studies may vary [L2082], [L27280].
Interestingly, zinc supplementation has become a critical intervention for treating diarrheal episodes in children. Studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions/salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for up to 12 weeks [L422].
More information about Zinc (in its natural form) is available at [DB01593].
|
| ATC Classification |
C05AX04
A12CB02
|
| IUPAC Name |
Zinc(2+) Ion Bis((2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanoate) |
| InChI |
Inchi=1S/2C6H12O7.Zn/C2*7-1-2(8)3(9)4(10)5(11)6(12)13;/H2*2-5,7-11H,1H2,(H,12,13);/Q;;+2/P-2/T2*2-,3-,4+,5-;/M11./S1 |
| InChI Key |
WHMDKBIGKVEYHS-IYEMJOQQSA-L |
| Canonical SMILES |
[Zn++].[H][C@@](O)(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]([H])(O)C([O-])=O.[H][C@@](O)(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]([H])(O)C([O-])=O |
| Useful Links |
DrugBank
ChEMBL
|