Drugs Information: Bortezomib

Basic Information

ID DDInter222
Drug Type small molecule
Molecular Formula C19H25Bn4O4
Molecular Weight 384.244
Description Bortezomib is a proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
ATC Classification L01XX32
IUPAC Name [(1R)-3-Methyl-1-[(2S)-3-Phenyl-2-(Pyrazin-2-Ylformamido)Propanamido]Butyl]Boronic Acid
InChI Inchi=1S/C19H25Bn4O4/C1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/H3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/T15-,17-/M0/S1
InChI Key GXJABQQUPOEUTA-RDJZCZTQSA-N
Canonical SMILES CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
Useful Links DrugBank ChEMBL PubChem

Interactions with Bortezomib

Severity level ID Name Mechanism Detail