Drugs Information: Cabozantinib

Basic Information

ID DDInter262
Drug Type small molecule
Molecular Formula C28H24Fn3O5
Molecular Weight 501.514
Description Cabozantinib is a tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer.
ATC Classification L01XE26
IUPAC Name N'1-{4-[(6,7-Dimethoxyquinolin-4-Yl)Oxy]Phenyl}-N1-(4-Fluorophenyl)Cyclopropane-1,1-Dicarboxamide
InChI Inchi=1S/C28H24Fn3O5/C1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/H3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)
InChI Key ONIQOQHATWINJY-UHFFFAOYSA-N
Canonical SMILES COC1=CC2=C(C=C1OC)C(OC1=CC=C(NC(=O)C3(CC3)C(=O)NC3=CC=C(F)C=C3)C=C1)=CC=N2
Useful Links DrugBank ChEMBL PubChem

Interactions with Cabozantinib

Severity level ID Name Mechanism Detail