|
| ID |
DDInter393 |
| Drug Type |
small molecule |
| Molecular Formula |
C38H69No13 |
| Molecular Weight |
747.964
|
| Description |
Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
|
| ATC Classification |
A02BD12
A02BD14
A02BD07
A02BD04
A02BD09
More
|
| IUPAC Name |
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyloxan-2-Yl]Oxy}-14-Ethyl-12,13-Dihydrox |
| InChI |
Inchi=1S/C38H69No13/C1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/H19-27,29-33,35,41-43,45H,15-18H2,1-14H3/T19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/M1/S1 |
| InChI Key |
AGOYDEPGAOXOCK-KCBOHYOISA-N |
| Canonical SMILES |
[H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]1[C@H](C)[C@@H](O[C@]2([H])O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@](C)(C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]1C)OC |
| Useful Links |
DrugBank
ChEMBL
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