|
| ID |
DDInter425 |
| Drug Type |
small molecule |
| Molecular Formula |
C21H21F3In3O2 |
| Molecular Weight |
531.316
|
| Description |
Cobimetinib is an antineoplastic agent and selective inhibitor of the mitogen-activated extracellular kinase (MEK) pathway used to treat unresectable or metastatic melanoma.
|
| ATC Classification |
L01XE38
|
| IUPAC Name |
1-{3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzoyl}-3-[(2S)-Piperidin-2-Yl]Azetidin-3-Ol |
| InChI |
Inchi=1S/C21H21F3In3O2/C22-14-6-5-13(19(18(14)24)27-16-7-4-12(25)9-15(16)23)20(29)28-10-21(30,11-28)17-3-1-2-8-26-17/H4-7,9,17,26-27,30H,1-3,8,10-11H2/T17-/M0/S1 |
| InChI Key |
BSMCAPRUBJMWDF-KRWDZBQOSA-N |
| Canonical SMILES |
OC1(CN(C1)C(=O)C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1)[C@@H]1CCCCN1 |
| Useful Links |
DrugBank
ChEMBL
PubChem
|