|
| ID |
DDInter62 |
| Drug Type |
small molecule |
| Molecular Formula |
C22H22N2O4 |
| Molecular Weight |
378.428
|
| Description |
Ambrisentan is a selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications.
|
| ATC Classification |
C02KX02
C02KX52
|
| IUPAC Name |
(2S)-2-[(4,6-Dimethylpyrimidin-2-Yl)Oxy]-3-Methoxy-3,3-Diphenylpropanoic Acid |
| InChI |
Inchi=1S/C22H22N2O4/C1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/H4-14,19H,1-3H3,(H,25,26)/T19-/M1/S1 |
| InChI Key |
OUJTZYPIHDYQMC-LJQANCHMSA-N |
| Canonical SMILES |
COC([C@H](OC1=NC(C)=CC(C)=N1)C(O)=O)(C1=CC=CC=C1)C1=CC=CC=C1 |
| Useful Links |
DrugBank
ChEMBL
PubChem
|