Drugs Information: Eltrombopag

Basic Information

ID DDInter631
Drug Type small molecule
Molecular Formula C25H22N4O4
Molecular Weight 442.475
Description Eltrombopag is a thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
ATC Classification B02BX05
IUPAC Name 3'-{2-[(4Z)-1-(3,4-Dimethylphenyl)-3-Methyl-5-Oxo-4,5-Dihydro-1H-Pyrazol-4-Ylidene]Hydrazin-1-Yl}-2'-Hydroxy-[1,1'-Biphenyl]-3-C
InChI Inchi=1S/C25H22N4O4/C1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/H4-13,26,30H,1-3H3,(H,32,33)/B27-22-
InChI Key XDXWLKQMMKQXPV-QYQHSDTDSA-N
Canonical SMILES CC1=NN(C(=O)\C1=N/NC1=CC=CC(C2=CC=CC(=C2)C(O)=O)=C1O)C1=CC=C(C)C(C)=C1
Useful Links DrugBank ChEMBL PubChem

Interactions with Eltrombopag

Severity level ID Name Mechanism Detail