Drugs Information: Entecavir

Basic Information

ID DDInter647
Drug Type small molecule
Molecular Formula C12H15N5O3
Molecular Weight 277.284
Description Entecavir is a nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases.
ATC Classification J05AF10
IUPAC Name 2-Amino-9-[(1S,3R,4S)-4-Hydroxy-3-(Hydroxymethyl)-2-Methylidenecyclopentyl]-6,9-Dihydro-3H-Purin-6-One
InChI Inchi=1S/C12H15N5O3/C1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/H4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/T6-,7-,8-/M0/S1
InChI Key QDGZDCVAUDNJFG-FXQIFTODSA-N
Canonical SMILES NC1=NC(=O)C2=C(N1)N(C=N2)[C@H]1C[C@H](O)[C@@H](CO)C1=C
Useful Links DrugBank ChEMBL PubChem

Interactions with Entecavir

Severity level ID Name Mechanism Detail