Drugs Information: Everolimus
Basic Information
|
||
| ID | DDInter704 | |
| Drug Type | small molecule | |
| Molecular Formula | C53H83No14 | |
| Molecular Weight | - | |
| Description | Everolimus is a mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies. | |
| ATC Classification | L01XE10 L04AA18 | |
| IUPAC Name | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-Hydroxyethoxy)-3-Methoxyc | |
| InChI | Inchi=1S/C53H83No14/C1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/H11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/B13-11+,16-12+,33-17+,37-27+/T32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/M1/S1 | |
| InChI Key | HKVAMNSJSFKALM-GKUWKFKPSA-N | |
| Canonical SMILES | [H][C@@]1(C[C@@H](C)[C@]2([H])CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@]3([H])CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@@]3([H])C(=O)O2)OC)CC[C@@H](OCCO)[C@@H](C1)OC | |
| Useful Links | DrugBank ChEMBL PubChem | |
Interactions with Everolimus
| Severity level | ID | Name | Mechanism | Detail |
|---|