Drugs Information: Exemestane

Basic Information

ID DDInter705
Drug Type small molecule
Molecular Formula C20H24O2
Molecular Weight 296.410
Description Exemestane is an aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
ATC Classification L02BG06
IUPAC Name (1S,2R,10R,11S,15S)-2,15-Dimethyl-8-Methylidenetetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]Heptadeca-3,6-Diene-5,14-Dione
InChI Inchi=1S/C20H24O2/C1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/H6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/T14-,15-,16-,19+,20-/M0/S1
InChI Key BFYIZQONLCFLEV-DAELLWKTSA-N
Canonical SMILES [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC(=C)C2=CC(=O)C=C[C@]12C
Useful Links DrugBank ChEMBL PubChem

Interactions with Exemestane

Severity level ID Name Mechanism Detail