Drugs Information: Fidaxomicin
Basic Information
|
||
| ID | DDInter734 | |
| Drug Type | small molecule | |
| Molecular Formula | C52H74Cl2O18 | |
| Molecular Weight | - | |
| Description | Fidaxomicin is a macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection. | |
| ATC Classification | A07AA12 | |
| IUPAC Name | (2R,3S,4S,5S,6R)-6-{[(3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-{[(2R,3S,4R,5S)-3,4-Dihydroxy-6,6-Dimethyl-5-[(2-Methylpropanoyl)Oxy]O | |
| InChI | Inchi=1S/C52H74Cl2O18/C1-13-30-22-26(6)33(56)18-16-15-17-31(23-66-51-45(65-12)42(61)44(29(9)67-51)69-49(64)35-32(14-2)36(53)39(58)37(54)38(35)57)48(63)68-34(28(8)55)20-19-25(5)21-27(7)43(30)70-50-41(60)40(59)46(52(10,11)72-50)71-47(62)24(3)4/H15-17,19,21-22,24,28-30,33-34,40-46,50-51,55-61H,13-14,18,20,23H2,1-12H3/B16-15+,25-19+,26-22+,27-21+,31-17+/T28-,29-,30+,33+,34+,40-,41+,42+,43+,44-,45+,46+,50-,51-/M1/S1 | |
| InChI Key | ZVGNESXIJDCBKN-UUEYKCAUSA-N | |
| Canonical SMILES | [H][C@@]1(O[C@@H]2[C@@H](CC)\C=C(C)\[C@@H](O)C\C=C\C=C(CO[C@@H]3O[C@H](C)[C@@H](OC(=O)C4=C(CC)C(Cl)=C(O)C(Cl)=C4O)[C@H](O)[C@@H]3OC)\C(=O)O[C@@H](C\C=C(/C)\C=C2/C)[C@@H](C)O)OC(C)(C)[C@@H](OC(=O)C(C)C)[C@H](O)[C@@H]1O | |
| Useful Links | DrugBank ChEMBL PubChem | |
Interactions with Fidaxomicin
| Severity level | ID | Name | Mechanism | Detail |
|---|