Drugs Information: Gilteritinib
Basic Information
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| ID | DDInter817 | |
| Drug Type | small molecule | |
| Molecular Formula | C29H44N8O3 | |
| Molecular Weight | 552.724 | |
| Description | Gilteritinib is an AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia. | |
| ATC Classification | L01XE54 | |
| IUPAC Name | 6-Ethyl-3-({3-Methoxy-4-[4-(4-Methylpiperazin-1-Yl)Piperidin-1-Yl]Phenyl}Amino)-5-[(Oxan-4-Yl)Amino]Pyrazine-2-Carboxamide | |
| InChI | Inchi=1S/C29H44N8O3/C1-4-23-28(31-20-9-17-40-18-10-20)34-29(26(33-23)27(30)38)32-21-5-6-24(25(19-21)39-3)37-11-7-22(8-12-37)36-15-13-35(2)14-16-36/H5-6,19-20,22H,4,7-18H2,1-3H3,(H2,30,38)(H2,31,32,34) | |
| InChI Key | GYQYAJJFPNQOOW-UHFFFAOYSA-N | |
| Canonical SMILES | CCC1=C(NC2CCOCC2)N=C(NC2=CC=C(N3CCC(CC3)N3CCN(C)CC3)C(OC)=C2)C(=N1)C(N)=O | |
| Useful Links | DrugBank ChEMBL PubChem | |
Interactions with Gilteritinib
| Severity level | ID | Name | Mechanism | Detail |
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