Drugs Information: Halofantrine

Basic Information

ID DDInter852
Drug Type small molecule
Molecular Formula C26H30Cl2F3No
Molecular Weight 500.432
Description Halofantrine is an antimalarial used for the treatment of severe malaria.
ATC Classification P01BX01
IUPAC Name 3-(Dibutylamino)-1-[1,3-Dichloro-6-(Trifluoromethyl)Phenanthren-9-Yl]Propan-1-Ol
InChI Inchi=1S/C26H30Cl2F3No/C1-3-5-10-32(11-6-4-2)12-9-25(33)23-16-22-21(14-18(27)15-24(22)28)20-13-17(26(29,30)31)7-8-19(20)23/H7-8,13-16,25,33H,3-6,9-12H2,1-2H3
InChI Key FOHHNHSLJDZUGQ-UHFFFAOYSA-N
Canonical SMILES CCCCN(CCCC)CCC(O)C1=C2C=CC(=CC2=C2C=C(Cl)C=C(Cl)C2=C1)C(F)(F)F
Useful Links DrugBank ChEMBL PubChem

Interactions with Halofantrine

Severity level ID Name Mechanism Detail