Drugs Information: Itraconazole

Basic Information

ID DDInter995
Drug Type small molecule
Molecular Formula C35H38Cl2N8O4
Molecular Weight 705.647
Description Itraconazole is an antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
ATC Classification J02AC02
IUPAC Name 1-(Butan-2-Yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-Dichlorophenyl)-2-[(1H-1,2,4-Triazol-1-Yl)Methyl]-1,3-Dioxolan-4-Yl]Methoxy}Phenyl)Pi
InChI Inchi=1S/C35H38Cl2N8O4/C1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/H4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3/T25?,31-,35-/M0/S1
InChI Key VHVPQPYKVGDNFY-ZPGVKDDISA-N
Canonical SMILES CCC(C)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(OC[C@H]2CO[C@@](CN3C=NC=N3)(O2)C2=CC=C(Cl)C=C2Cl)C=C1
Useful Links DrugBank PubChem

Interactions with Itraconazole

Severity level ID Name Mechanism Detail