Drugs Information: Auranofin

Basic Information

ID DDInter139
Drug Type small molecule
Molecular Formula C20H34Auo9Ps
Molecular Weight 678.490
Description Auranofin is an antirheumatic used to treat active, progressive, or destructive forms of inflammatory arthritis.
ATC Classification M01CB03
IUPAC Name [(2R,3R,4S,5R,6S)-3,4,5-Tris(Acetyloxy)-6-{[(Triethyl-Lambda5-Phosphanylidene)Aurio]Sulfanyl}Oxan-2-Yl]Methyl Acetate
InChI Inchi=1S/C14H20O9S.C6H15P.Au/C1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/H10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/Q;;+1/P-1/T10-,11-,12+,13-,14+;;/M1../S1
InChI Key AUJRCFUBUPVWSZ-XTZHGVARSA-M
Canonical SMILES CCP(CC)(CC)=[Au]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O
Useful Links DrugBank PubChem

Interactions with Auranofin

Severity level ID Name Mechanism Detail