Interaction between Cefotaxime and Nystatin
Unknown Unknown

ID DDInter323 and DDInter1318
Interaction
Amnesia bronchiolitis confusion Cough patent ductus arteriosis ischaemia black stools narcolepsy nystagmus loss of consciousness More
Management -
References
Alternative for Cefotaxime J01D
Meropenem
Cefradine
Ertapenem
Doripenem
Cefditoren
Cefamandole
Cefotetan
Cefalotin
Ceftaroline fosamil
Cefoxitin
Ceftibuten
More
Alternative for Nystatin D01A
Ciclopirox
Miconazole (topical)
Chlorphenesin
Econazole
Tioconazole
Flucytosine
Terbinafine
Salicylic acid (topical)
Griseofulvin
Ketoconazole
Clotrimazole
More

Potential Metabolism Interactions

Substrate-Substrate Interaction：If more than one drug is metabolized by the same CYP, it is possible that its metabolism is inhibited because of the competition between the drugs. That means, it can be useful to lower the dosage of the drugs in the drug-cocktail because they remain longer in the organism than in monotherapy.
Inhibitor-Inhibitor Interaction：Combining two or more inhibitors of one CYP, should be compensated by lowering the dosage of these drugs because the metabolism is reduced and the drugs remain longer in the organism than in monotherapy. Not adapting the dosage bears the risk of even more side effects.
Inhibitor-Substrate Interaction：Combining drugs that have inhibitory effect and are substrates of one particular CYP, should be compensated by lowering the dosage. They rest longer in the organism than in monotherapy. Not adapting the dosage bears the risk of even more side effects.