Interaction between Losartan and Econazole
Unknown
Unknown
ID | DDInter1095 and DDInter616 |
Interaction |
Anxiety
arthritis
Arthritis rheumatoid
Back Ache
bronchial spasm
bronchitis
pleural pain
cholelithiasis
confusion
Cough
More
|
Management | - |
References | |
Alternative for Losartan |
C09C
C09D
More
|
Alternative for Econazole |
G01A
Brinzolamide (ophthalmic)
Vemurafenib
Diazoxide
Trichlormethiazide
Chloramphenicol (otic)
Chloramphenicol (ophthalmic)
Sulfamethoxazole
Dorzolamide (ophthalmic)
Amphotericin B (lipid complex)
Metronidazole (topical)
Miconazole (topical)
More
|
Potential Metabolism Interactions
Substrate-Substrate Interaction:If more than one drug is metabolized by the same CYP, it is possible that its metabolism is inhibited because of the competition between the drugs. That means, it can be useful to lower the dosage of the drugs in the drug-cocktail because they remain longer in the organism than in monotherapy.
Inhibitor-Inhibitor Interaction:Combining two or more inhibitors of one CYP, should be compensated by lowering the dosage of these drugs because the metabolism is reduced and the drugs remain longer in the organism than in monotherapy. Not adapting the dosage bears the risk of even more side effects.
Inhibitor-Substrate Interaction:Combining drugs that have inhibitory effect and are substrates of one particular CYP, should be compensated by lowering the dosage. They rest longer in the organism than in monotherapy. Not adapting the dosage bears the risk of even more side effects.